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Safety Recommendations for Administering Intravenous Prostacyclins in the Hospital

Author(s): Martha S. Kingman, DNP, FNP-C; Kelly Chin, MD

Contact Hours: 1.00

CERP A: 1.00

Expires Oct 01, 2017

Topics: MedicationManagement, PulmonaryPatientSafety

Population: Adult

Role: Staff

Member: Free
NonMember: $10.00

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Activity Summary

Prostacyclins are a high-risk category of continuous intravenous infusions increasingly used in hospitals to treat advanced pulmonary arterial hypertension, a rare condition characterized by vasoconstriction and vascular proliferation of the pulmonary arteries. Prostacyclins are given in doses of nanograms per kilogram per minute and have a narrow therapeutic dosing range for each patient. Sudden increases or decreases in dose can be life threatening. Previous studies revealed errors in the administration of these high-risk infusions, which in some instances led to serious adverse events, including death. We reviewed the literature for safety measures in administration of high-risk intravenous medications and obtained input from leading experts in pulmonary arterial hypertension to create


  • Distinguish between adverse effects of prostacyclins and symptoms of pulmonary artery hypertension
  • Summarize 4 approaches to prevent errors associated with high-risk medications
  • Describe 3 safety recommendations that reduce error during prostacyclin administration

Continuing Education Disclosure Statement

Successful Completion

Learners must attend/view/read the entire activity and complete the associated evaluation to be awarded the contact hours or CERP. No partial credit will be awarded.


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