Norepinephrine Dosing in Obese and Nonobese Patients With Septic Shock

Author(s): John J. Radosevich, PharmD, Asad E. Patanwala, PharmD, and Brian L. Erstad, PharmD

Contact Hours 1.00

CERP A 1.00

Pharmacology Hours 1.00

Expires Jan 01, 2019

Topics: Pharmacology, Sepsis

Population: Adult

Role: Staff, APRN

Fees
Member: Free
NonMember: $10.00

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Activity Summary

Whether or not norepinephrine infusions for support of hemodynamic status in patients with septic shock should be weight based is unknown. This situation is particularly pertinent in patients who are extremely overweight or obese.

Objectives

  • Identify logistical issues and challenges with using weight-based dosing of norepinephrine in the obese.
  • Determine if non-weight based dosing and titration of norepinephrine is appropriate in obese patients.
  • Explain the relationship between drug concentrations of norepinephrine and effect on mean arterial pressure.

Continuing Education Disclosure Statement

Successful Completion

Learners must attend/view/read the entire activity and complete the associated evaluation to be awarded the contact hours or CERP. No partial credit will be awarded.

Disclosure

This activity has been reviewed by the Nurse Planner. It has been determined that the material presented here shows no bias. Approval of a continuing education activity does not imply endorsement by AACN or ANCC of any commercial products displayed or discussed in conjunction with the activity.

Accreditation

The American Association of Critical-Care Nurses (AACN) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s (ANCC's) Commission on Accreditation, ANCC Provider Number 0012 (60 min contact hour). AACN has been approved as a provider of continuing education in nursing by the California State Board of Nursing, California Provider number CEP01036 for 1.2 contact hours (50 min contact hour).

AACN programming meets the standards for most states that require mandatory continuing education contact hours for license and/or certification renewal. AACN recommends consulting with your state board of nursing or credentialing organization before submitting CE to fulfill continuing education requirements.