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Ketorolac as an Analgesic Agent for Infants and Children After Cardiac Surgery

Author(s): Meredith K. Jalkut, RN, MSN, CRNP

Contact Hours: 1.00

CERP A: 1.00

Pharmacology Hours: 1.00

Expires Jan 01, 2017

Topics: Pharmacology, PainManagement

Population: Neonatal, Pediatric

Role: Staff, APRN

Member: Free
NonMember: $10.00

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Activity Summary

Ketorolac has been used safely as an analgesic agent for children following cardiac surgery in selected populations. Controversy exists among institutions about the risks involved with this medication in this patient oup. This article reviews the current literature regarding the safety of ketorolac for postoperative pain management in children after cardiac surgery. Specifically, concerns about renal dysfunction and increased bleeding risk are addressed. Additionally, the article details pharmacokinetics and potential benefits of ketorolac, such as its opioidsparing effect. The literature reflects that the use of this medication is not well studied in certain pediatric cardiac patients such as neonates and those with single-ventricle physiology, and the safety of this medication in regards to these special populations is reviewed. In conclusion, ketorolac can be used in specific pediatric patients after cardiac surgery with minimal risk of bleeding or renal dysfunction with appropriate dosing and duration of use.


  • Identify information from current literature that supports the safe use of ketorolac in the pediatric population after cardiac surgery.
  • Review the most common conditions in which ketorolac should not be used in the pediatric population after cardiac surgery.
  • Discuss the appropriate dosing of ketorolac in the pediatric population after cardiac surgery.

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