Factors Associated With Initiation of Mechanical Ventilation in Patients With Sepsis: Retrospective Observational Study

Author(s): Robert E. Freundlich, MD, MS, MSCI, Gen Li, MStat, MChem, Aleda Leis, PhD, and Milo Engoren, MD

Contact Hours 1.00

CERP A 1.00

Expires Sep 01, 2026

Topics: Pulmonary, Sepsis

Population: Geriatric

Member: Free
NonMember: $10.00

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Activity Summary

Required reading for all learners: Implicit Bias impacts patient outcomes

Mechanical ventilation is frequently initiated in patients with sepsis to maintain alveolar ventilation and arterial oxygenation. Patients with sepsis have an increased risk of hemodynamic instability, depressed consciousness, and sepsis-induced acute respiratory failure. Although generally used with therapeutic intent, mechanical ventilation introduces risks that could worsen patient outcomes, and these risks increase in proportion to the duration of mechanical ventilation. Data from the electronic health record were used to model risk factors for initiation of mechanical ventilation after the onset of sepsis. Through a better understanding of risk factors for initiation of mechanical ventilation in patients with sepsis, targeted interventions may be tailored to high risk patients.


  • Identify risk factors for septic patients to require mechanical ventilation.
  • Describe how risk factors vary with time.
  • Analyze how to incorporate these findings into your clinical practice.

Continuing Education Disclosure Statement

Successful Completion

Learners must attend/view/read the entire activity, read Implicit Bias impacts patient outcomes, and complete the associated evaluation to be awarded the contact hours or CERP. No partial credit will be awarded.


The American Association of Critical-Care Nurses is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.

Provider approved by the California Board of Registered Nursing, Provider number CEP 1036, for 1.00 contact hours.

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