Article A26112
Author(s): Ariel Haber, PharmD, BCCCP, Ada Selina Jutba, PharmD, BCCCP, Haya Kaseer, PharmD, BCCCP, Moustafa Younis, MD, MSCR, and Ali Ataya, MD, MBA
Contact Hours 1.00
CERP A 1.00
Pharmacology Hours 1.00
Expires Nov 01, 2029
Topics: Pulmonary, Hematology/Oncology
Before you Begin
1. Reflect on the following question: What new knowledge or perspective do you hope to gain from this activity?
2. Review: Implicit Bias and its Impact on Patient Outcomes (License requirement for California)
Description
This article examines the ongoing debate over the optimal alteplase dose for patients with high-risk pulmonary embolism (PE), a condition associated with the highest short-term mortality among hospitalized patients. While alteplase is an approved thrombolytic therapy for PE, uncertainty remains regarding whether low-dose (50 mg) or standard-dose (100 mg) treatment provides the best balance of efficacy and safety. Using contemporary definitions of high-risk PE, including right ventricular dysfunction and hemodynamic instability, the study compares clinical outcomes between dosing strategies. The findings provide important insights for critical care clinicians managing patients with life-threatening PE and may help inform thrombolytic treatment decisions in this high-risk population.Learners must complete the entire activity and the associated evaluation AND read Implicit Bias impacts patient outcomes. No partial credit will be awarded.
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nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.
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