Finding the Right Dose: Optimizing Drug Therapy in Critically Ill Patients With Obesity

Author(s): Lauren Finch, PharmD, Carolyne DaSilva, PharmD, Uyen Diep, PharmD, BCCCP, FCCM

Contact Hours 1.00

CERP A 1.00

Pharmacology Hours 1.00

Expires Sep 01, 2029

Topics: MultiSystem, Pharmacology, Medication Management

Population: Adult

Role: APRN, Staff

Fees
Member: Free
NonMember: $10.00

Added to Collection

Activity Summary

Before you Begin

1. Reflect on the following question: What new knowledge or perspective do you hope to gain from this activity?

2. Review: Implicit Bias and its Impact on Patient Outcomes (License requirement for California)

Description

Obesity can significantly affect the absorption, distribution, metabolism, and elimination of medications, creating challenges for safe and effective drug therapy. Physiologic changes associated with excess body weight may alter medication response, making standard dosing strategies less reliable. Careful selection of dosing weight, consideration of drug-specific characteristics, and therapeutic drug monitoring are often necessary to optimize treatment outcomes while minimizing the risk of toxicity or treatment failure in patients with obesity.

Objectives

  • Identify pharmacokinetic and pharmacodynamic alterations in patients with obesity that influence medication dosing and therapeutic response.
  • Evaluate weight-based dosing impact on efficacy and safety and select appropriate body weight metric based on drug pharmacokinetics.
  • Recognize appropriate monitoring parameters and the timing of therapeutic drug monitoring to evaluate medication efficacy and safety.

Continuing Education Disclosure Statement

Criteria for Awarding Contact Hours

Learners must complete the entire activity and the associated evaluation AND read Implicit Bias impacts patient outcomes. No partial credit will be awarded.

Accreditation

American Association of Critical-Care Nurses is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.
Provider approved by the California Board of Registered Nursing, Provider number CEP 1036, for {contactHours} contact hours.

Disclosures

The Nurse Planner has determined that no individuals with the ability to control content of this activity have relevant relationships with ineligible companies.

Activities with pharmacotherapeutic credit are to assist the APRN in fulfilling their education requirements for licensure and certification renewals.

Refund Policy

Continuing Education Activities are nonrefundable.