New and Off-Label Uses of Tranexamic Acid

Author(s): Stephanie M. Johnson, PharmD, Dawn Tsang, PharmD, BCPS, Mary Dansby, PharmD, BCPS, Christopher Allen, PharmD, BCPS, BCNSP

Contact Hours 1.00

CERP A 1.00

Pharmacology Hours 1.00

Expires Aug 31, 2027

Topics: Pharmacology, Hemodynamics, Trauma

Fees
Member: Free
NonMember: $10.00

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Activity Summary

Required reading for all learners: Implicit Bias impacts patient outcomes

While the FDA approved uses of tranexamic acid are limited, off label use has applications to patients in critical care, particularly trauma and surgical patients. This article describes the mechanism of action of TXA and summarizes the research on off-label use. Considerations such as adverse events, the timing of administration and contraindications are also discussed.

Objectives

  • Describe the pharmacokinetics, safety, and approved indications for tranexamic acid
  • Evaluate the current evidence related to the off-label use of tranexamic acid in trauma-related bleeding, surgery, and postpartum hemorrhage
  • Identify the role of tranexamic acid in new off-label uses including hemoptysis and epistaxis

Continuing Education Disclosure Statement

Criteria for Awarding Contact Hours

Learners must complete the entire activity and the associated evaluation AND read Implicit Bias impacts patient outcomes. No partial credit will be awarded.

Accreditation

American Association of Critical-Care Nurses is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.
Provider approved by the California Board of Registered Nursing, Provider number CEP 1036, for {contactHours} contact hours.

Disclosures

The Nurse Planner has determined that no individuals with the ability to control content of this activity have relevant relationships with ineligible companies.

Activities with pharmacotherapeutic credit are to assist the APRN in fulfilling their education requirements for licensure and certification renewals.

Refund Policy

Continuing Education Activities are nonrefundable.